Tim Brunson DCH

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Thiamin Deficient Insomnia

Posted At : August 20, 2009 3:42 AM | Posted By : Tim Brunson, PhD
Related Categories: General


by Derrick Lonsdale, M.B.B.S.

An 84-year old man had sudden onset of chronic insomnia, localized palmar tenderness and "trigger finger" of the left hand ring finger. Laboratory studies indicated thiamin deficiency, increased inflammatory markers and fasting blood triglycerides. He discontinued sugar completely without changes in dietary supplements or life style. Gradual improvement in insomnia, trigger finger, weight loss and laboratory studies occurred over 6 months. Then a single minimal ingestion of simple carbohydrate resulted next day in increased blood triglycerides and thiamin pyrophosphate effect (TPPE) on transketolase activity (TKA).

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