Tim Brunson DCH

Welcome to The International Hypnosis Research Institute Web site. Our intention is to provide quality information to clinicians and the general public concerning hypnosis, hypnotherapy, and other mind/body modalities. We intend to expand our coverage to include such topics as Neuro-Linguistic Programming (NLP), energy psychology and medicine, and other related topics. While our intention is to provide quality information derived from valid sources, including peer reviewed literature concerning significant research, this site is not presented as a source of medical or psychological advice. Clinicians wishing to expand their scope of practice or protocols based upon presented information should perform due diligence prior to use. It is our sincere hope to stimulate interest in these topics and to contribute to the evolution of the science of hypnosis. -- Tim Brunson DCH

Effectiveness of complementary and self-help treatments for anxiety in children and adolescents.

To review the evidence for the effectiveness of complementary and self-help treatments for anxiety disorders and situational anxiety in children and adolescents. DATA SOURCES: Systematic literature search using PubMed, PsycINFO and the Cochrane Library for 111 treatments up to February 2006. STUDY SELECTION: There were 11 treatments for which intervention studies had been undertaken and reported. DATA EXTRACTION: Studies on each treatment were reviewed by one author and checked by a second. A consensus was reached for level of evidence. DATA SYNTHESIS: Relevant evidence was available for bibliotherapy, dance and movement therapy, distraction techniques, humour, massage, melatonin, relaxation training, autogenic training, avoiding marijuana, a mineral-vitamin supplement (EMPower +) and music therapy. Findings from case-control studies, individual cohort studies or low quality randomised controlled trials indicated that several treatments may have potential to reduce anxiety, including bibliotherapy, massage, melatonin, and relaxation training. CONCLUSIONS: Although some complementary and self-help treatments might be useful for children and adolescents with anxiety, they need to be tested adequately through randomised controlled trials before they could be recommended.

Med J Aust. 2008 Mar 17;188(6):355-9. Parslow R, Morgan AJ, Allen NB, Jorm AF, O'Donnell CP, Purcell R. Department of Psychiatry, University of Melbourne, Melbourne, VIC, Australia. rparslow@unimelb.edu.au.

Hypnotic abreaction releases chaotic patterns of electrodermal activity during dissociation.

Chaotic transitions emerge in a wide variety of cognitive phenomena and may possibly be linked to specific changes during development of mental disorders. There are several hypotheses that link the dissociation to critical chaotic shifts with the resulting self-organization of behavioral patterns during critical periods. In 2 patients, hypnotic revivification of dissociated trauma along with measurement of bilateral electrodermal activity (EDA) for therapeutic and research purposes was performed. Nonlinear data analysis of EDA records shows a difference between degree of chaos in hypnotic relaxed state before revivification of the trauma and dissociated state after reliving the traumatic memory. Results suggest that the dissociated state after revivification of the trauma is significantly more chaotic than the state during the hypnotic relaxation before the event. Findings of this study suggest a possible role of neural chaos in the processing of the dissociated traumatic memory during hypnotic revivification.

Int J Clin Exp Hypn. 2007 Oct;55(4):435-56. Bob P. Department of Psychiatry, 1st Faculty of Medicine, Charles University, Prague, Czech Republic. petrbob@netscape.net

User friendly hypnosis as an adjunct for treatment of habit cough: a case report.

The more user friendly medical hypnosis can be, the more readily it will be accepted by patients and the medical community. Hypnosis is user friendly when it is simple to employ, and yields rapid, effective, and clinically significant results. Thus, we should define reasons for the effectiveness of such successful hypnosis methods, and provide this information to students of hypnosis. Some of the elements that may permit hypnosis to be user friendly are establishment of rapport, a belief that a symptom often has a functional role, and a flexible approach to the hypnosis encounter. This case report of a child with habit cough, illustrates the importance of these elements.

Am J Clin Hypn. 2007 Oct;50(2):171-5. Anbar RD. SUNY Upstate Medical University, Syracuse, NY 13210, USA. anbarr@upstate.edu

An exploratory outcome comparison between an Ericksonian approach.

The purpose of this study was to determine whether an Ericksonian approach to therapy using hypnosis (ET) was as effective as brief dynamic therapy (BDT), a long-standing and well-researched form of psychotherapy. The study used a comparative pretest/posttest design with four paper and pencil tests [Clark Personal and Social Adjustment Scale (CPSAS), Hopkins Symptom Checklist (HSCL), Target Complaint (TC), and Global Improvement (GI)] and six therapy sessions. The investigators attempted to choose design features that would not interfere with the unique qualities of ET while maintaining empirical regularity. No statistically significant difference was found except on HSCL where ET was superior. An interesting finding was that without direct discussion of the target complaint, ET brought about the same improvement on targeted problems as BDT. ET subjects reported gaining understanding of their problems as much as BDT subjects, but from a different source. The results of this study are a step toward empirical confirmation of ET as an evidence-based treatment alternative for psychotherapy.

Am J Clin Hypn. 2008 Jan;50(3):217-32. Simpkins CA, Simpkins AM. AMCAS123@aol.com

Hypnosis-provoked nonepileptic events in children.

The purpose of this study was to describe the use of hypnotic suggestion as a means of precipitating nonepileptic events in children while they are undergoing video electroencephalographic monitoring (VEEG) for differential diagnosis of seizurelike behavior. METHODS: Nine children aged 8-16 years were referred for VEEG to differentiate between epileptic seizures and nonepileptic events. All subjects underwent psychiatric consultation. Hypnosis was attempted in all subjects to try to provoke typical seizurelike events. RESULTS: In eight of nine patients, their typical seizurelike events were provoked by hypnosis. In all eight children, video and EEG analysis of the provoked events demonstrated them to be nonepileptic. No epileptiform abnormalities were present on interictal EEGs. No epileptic seizures occurred. CONCLUSION: Hypnosis is a useful and ethical means of provoking psychogenic nonepileptic events in children. Hypnotic suggestion should be considered as a provocative method when possibly psychogenic nonepileptic events have not occurred spontaneously during diagnostic evaluation.

Epilepsy Behav. 2008 Jan 11 Olson DM, Howard N, Shaw RJ. Department of Neurology, Stanford University School of Medicine, Stanford, CA, USA; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA.

The treatment of parasomnias with hypnosis: a 5-year follow-up study.

This study involves a replication and extension of a previous one reported by Hurwitz et al (1991) on the treatment of certain parasomnias with hypnosis.

METHODS: Thirty-six patients (17 females), mean age 32.7 years (range 6-71). Four were children aged 6 to 16. All had chronic, "functionally autonomous" (self-sustaining) parasomnias. All underwent 1 or 2 hypnotherapy sessions and were then followed by questionnaire for 5 years. RESULTS: Of the 36 patients, 45.4% were symptom-free or at least much improved at the 1-month follow-up, 42.2% at the 18-month follow-up, and 40.5% at the 5-year follow-up. CONCLUSIONS: One or 2 sessions of hypnotherapy might be an efficient first-line therapy for patients with certain types of parasomnias.

J Clin Sleep Med. 2007 Jun 15;3(4):369-73. Hauri PJ, Silber MH, Boeve BF. Sleep Disorders Center, Mayo Clinic College of Medicine, Rochester, MN 55905, USA. hauri.peter@mayo.edu

Releasing Phobia's and Traumatic Events FAST

by Wil Horton, Psy. D. CAC CMI

As I was thinking about what to write for this article, I received a phone call from a rather distraught young man. He was quite upset that he had to leave his job as an iron worker because he was having severe panic attacks whenever he went above a couple of stories. As I gathered information, I found that he had avoided jobs for a couple of years that would require heights. As we made an appointment, I knew that he would need a Phobia relief technique, and I could use this as a teaching tool for this article.

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Why Would You Say “WHEE!” When You’re Stressed?

by Daniel J. Benor, M.D.

I am a frustrated psychiatrist. I trained back in the years when psychiatry was all psychotherapy. I continue to have a passion to help people deal with their problems through talking therapy – but Psychiatry has changed over the years into being only focused on prescribing medications. To maintain my own sanity, and to be able to continue to help people who came to me with the sorts of problems described below, I develop WHEE. WHEE is a potent, new, self-healing method that relieves stress and distress within minutes. Once you know this method, you can de-stress any time you want to. Its effects are deep and permanent.

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Hypnosis and Addictions

Hypnosis has been commonly recognized as an effective intervention in the treatment of obsessions, compulsions, and addictions. It may not be for the reasons that we normally think. Too often efficacious findings are coupled with head scratching admissions pertaining to the lack of understanding of the causality. Modern findings and recent discoveries by neuroscientists may open the door for understanding the relationship between hypnosis and the treatment of addictions. Suggestions of relaxation and slow, calm breathing as promoted by hypnosis, meditation, and yoga are significant factors in the treatment of addictions.

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Stress-free Festive Season: 3 Keys to maximize your holiday-enjoyment

by Brian Walsh, Ph.D.

What is most challenging for you in the time leading up to the year-end festivities? Is it shopping, or social obligations, or preparing large meals, or maybe just too much to do and so little time to do it? Well, I'm here to dish out a few bits of advice that may seem a bit odd at first, but please bear with me.

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Hypnosis for schizophrenia.

Many people with schizophrenia continue to experience symptoms despite conventional treatments being used. Alternative therapies such as hypnosis, in conjunction with conventional treatments, may be helpful. OBJECTIVES: To investigate the use of hypnosis for people with schizophrenia or schizophrenia-like illnesses compared with standard care and other interventions. SEARCH STRATEGY: We searched the Cochrane Schizophrenia Group's Register (October 2006), contacted the Cochrane Complementary Medicine Field for additional searching (January 2003), hand searched references of included or excluded studies and made personal contact with authors of relevant trials. SELECTION CRITERIA: We included all randomised or double blind controlled trials that compared hypnosis with other treatments or standard care for people with schizophrenia. DATA COLLECTION AND ANALYSIS: We reliably selected studies, quality assessed them and extracted data. We excluded data where more than 50% of participants in any group were lost to follow up. For binary outcomes we calculated a fixed effects risk ratio (RR) and its 95% confidence interval (CI). MAIN RESULTS: We included three studies (total n=149). When hypnosis was compared with standard treatment no one left the studies between 1-8 weeks (n=70, 2 RCTs, Risk Difference 0.00 CI -0.09 to 0.09). Mental state scores were unaffected (n=60, 1 RCT, MD BPRS by one week -3.6 CI -12.05 to 4.8) as were measures of movement disorders and neurocognitive function. Compared with relaxation, hypnosis was also acceptable (n=106, 3 RCTs, RR leaving the study early 2.00 CI 0.2 to 2.15) and had no discernable effect on mental state (n=60, 1 RCT, MD BPRS by one week -3.4 CI -11.4 to 4.6), movement disorders or neurocognitive function. Hypnosis was as acceptable as music (Sibelius) by four weeks (n=36, RR leaving the study early 5.0, CI 0.3 to 97.4). AUTHORS' CONCLUSIONS: The studies in this field are few, small, poorly reported and outdated. Hypnosis could be helpful for people with schizophrenia. If we are to find this out, better designed, conducted and reported randomised studies are required. This current update has not revealed any new studies in this area since 2003.

Cochrane Database Syst Rev. 2007 Oct 17;(4):CD004160. Izquierdo de Santiago A, Khan M.

Color: Its Therapeutic Power for Rapid Healing.

by Steven R. Vazquez, Ph.D.

(This is an abstract from an article which appeared in Subtle Energies & Energy Medicine Volume Seventeen, Number Two)

New breakthroughs in the use of color as a healing agent for rapid recovery of trauma, depression, physical pain and spiritual blockages have elevated the power of color for healing. These historical, religious and neurophysiological contexts of color are reviewed herein. Then factors of length of viewing time, brightness, saturation, visual depth perception, angle of viewing, hue, strobic emission and the emotional state of the subject at the time of viewing are elaborated as critical issues that amplify therapeutic effects. When these factors are combines with the recent findings of interpersonal neurobiology to facilitate processes with color a new synthesis for rapid transformation is achieved.

Steven Vazquez 1241 Southridge Court, Suite 105. Hurst, TX 76053 srv@lightworkassociates.com

For more information visit www.LightWorkAssociated.com.

Effects of Binaural-Beat Stimulation on Recovery Following Traumatic Brain Injury: A Pilot Study.

by Signe Klepp, O.T.

(This is an abstract from an article which appeared in Subtle Energies & Energy Medicine Volume Seventeen, Number Two)

Patients suffering from traumatic brain injury (TBI) lose the ability to structure their own life. Rehabilitation is expensive in time, money and effort. A noninvasive, patient-controlled method, binaural-beat auditory stimulation, may elicit changes in states if consciousness and mood. This study assesses the feasibility and efficacy of using this method to improve self-esteem, quality of life and function of daily living for persons suffering from old TBI.

Signe Klepp - amps@kleppconsult.no

Hypnosis for schizophrenia.

Many people with schizophrenia continue to experience symptoms despite conventional treatments being used. Alternative therapies such as hypnosis, in conjunction with conventional treatments, may be helpful. OBJECTIVES: To investigate the use of hypnosis for people with schizophrenia or schizophrenia-like illnesses compared with standard care and other interventions. SEARCH STRATEGY: We searched the Cochrane Schizophrenia Group's Register (October 2006), contacted the Cochrane Complementary Medicine Field for additional searching (January 2003), hand searched references of included or excluded studies and made personal contact with authors of relevant trials. SELECTION CRITERIA: We included all randomised or double blind controlled trials that compared hypnosis with other treatments or standard care for people with schizophrenia. DATA COLLECTION AND ANALYSIS: We reliably selected studies, quality assessed them and extracted data. We excluded data where more than 50% of participants in any group were lost to follow up. For binary outcomes we calculated a fixed effects risk ratio (RR) and its 95% confidence interval (CI). MAIN RESULTS: We included three studies (total n=149). When hypnosis was compared with standard treatment no one left the studies between 1-8 weeks (n=70, 2 RCTs, Risk Difference 0.00 CI -0.09 to 0.09). Mental state scores were unaffected (n=60, 1 RCT, MD BPRS by one week -3.6 CI -12.05 to 4.8) as were measures of movement disorders and neurocognitive function. Compared with relaxation, hypnosis was also acceptable (n=106, 3 RCTs, RR leaving the study early 2.00 CI 0.2 to 2.15) and had no discernable effect on mental state (n=60, 1 RCT, MD BPRS by one week -3.4 CI -11.4 to 4.6), movement disorders or neurocognitive function. Hypnosis was as acceptable as music (Sibelius) by four weeks (n=36, RR leaving the study early 5.0, CI 0.3 to 97.4). AUTHORS' CONCLUSIONS: The studies in this field are few, small, poorly reported and outdated. Hypnosis could be helpful for people with schizophrenia. If we are to find this out, better designed, conducted and reported randomised studies are required. This current update has not revealed any new studies in this area since 2003.

Cochrane Database Syst Rev. 2007 Oct 17 Izquierdo de Santiago A, Khan M.

Bispectral index monitoring during dissociative pseudo-seizure.

Severe forms of dissociation or conversion can lead to events clinically often described as pseudo-seizures. Borderline personality disorder is a clinical condition which is often accompanied by a high susceptibility for dissociation and dissociative states are characterized by memory disturbance and perceptual alterations. We report a case of a patient with a complete anaesthesia, paralysis and amnesia for about 1 h. Within this time period we measured a bispectrum EEG index called BIS. Deepest recorded BIS value was 47. The described pattern of short but deep BIS reductions is completely discongruent to the findings during physiological sleep, during general anaesthesia, but very similar (and even more pronounced) to those during self-hypnosis. This makes former assumptions plausible that hypnosis and severe forms of dissociation (or conversion) may share common aetiologies.

World J Biol Psychiatry. 2007 Sep 12;:1-3

Sartorius A, Schmahl C., Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Mannheim, Germany.

How To Forgive

by Michelle Beaudry, CHt

Make The Change Happen How are you going to do it, my friend? You're all done feeling wretched all the time, you know forgive does not mean forget, you are soooo ready, but you need a plan. Read on, my friend, and find out how to get the benefits of forgiveness for yourself. Right now.

Guilt and Hatred Are Killers Ask any doctor. Stress is a killer. This is because your body and mind are a continuum. In other words, although they are not entirely the same, a great overlap exists that unites them. Relieve your mental stress and your body will be happier too. Nothing relieves mental stress like forgiveness. Guilt and hatred resolve nothing; they just sustain the negativity that continues to obstruct you from your goals. Forgiveness, on the other hand, undoes the stickiness that binds you to an unhappy past.

Does It Work? Absolutely - for you. Since the forgiveness experience will happen only for you, only you will receive its benefits. Your forgiveness may not influence a change in the behavior of others one bit. But it's not about them. It's about you. Forgiveness is about generating your own healing. You are the only player in your life over whom you have all the power. It's time to exercise your personal power, your right to choose to feel better about who you are, your right to process your past and move on with your life.

It's a Private Thing Since forgiving is all about you getting your own heart clear, it's best done in the privacy of your own mind. Afterwards you'll have the choice of telling others, if you like, but initially the process works best in solitude. Tell no one, just do the work. And watch how easy it is to feel better all day every day. Contrast this to the fact that all the pity parties in the world with your friends and relatives never made you feel better one bit. Those tactics don't work because they don't process emotions, they merely create a feedback loop that deepens the groove of the pain. Since you know that what you used to do didn't work, it's time to do what does.

Forgive in Steps Like a pyramid, forgiveness may seem overwhelming at first, but it's easily accomplished step by step. So begin by recognizing that there are three sections:

.forgiveness of others .self-forgiveness .receiving forgiveness from others

And these can be further broken down into nicely manageable chunks.

Forgiveness of Others When you forgive others in categories, it proceeds more easily. For example, you could choose to use the categories of Strangers, Friends, Family, The People who Hurt You The Most, and Anybody Else. You may include additional categories like Exlovers, Neighbors, Coworkers, Employees, etc., and some forgivers need to add the category of Humanity Itself. And you can start with the categories you find easiest. Once you notice how good it feels to forgive, this will inspire you to forgive everyone as much as possible, as fully as you can.

Self Forgiveness In this step, start with your earliest years and ascend: Newborn, three year old, five year old, ten year old, teenager, 20s, etc., and on up to your current age, forgiving yourself thoroughly for absolutely everything as you go. Once you get to your current age, forgive yourself for your whole life. Remember, all humans are flawed. No one is a perfect son or daughter, man or woman, husband or wife, student or teacher, worker or boss. You are allowed to make mistakes and learn from them. Forgiveness is an optimal method to process your learnings.

Receiving Forgiveness from Others In the privacy of your own mind, visualize then apologize to folks you've wronged, and let them accept your apology. It may surprise you to learn that others really want to forgive you. They do. So let them forgive you and receive the cleansing of that forgiveness. Afterwards, with some people, you may elect to actually apologize to them in person, but proceed carefully. There are a few folks in the world who can not accept apologies in real life, and this is why you process all of your apologies in your mind's eye thoroughly first, so that you get the emotional benefit of having apologized whether those apologies get accepted in real life or not.

Forgive by Percentages in Repeated Attempts Can you forgive the people who hurt you the most 10%? 20%? 80%? 99.9%? It's not all or nothing. Ease on up to higher and higher percentages, always aiming for 100% forgiveness, but being real with yourself. If the people who hurt you the most are not 100% forgiveable on your first attempt, continue forgiving them bit by bit till you get as close to full forgiveness as possible. Start with a realistic percentage, then increase your forgiveness on subsequent attempts, always aiming for 100%. Just do your best.

Forgiving People Versus Events It can be one thing to forgive individual people, and can yet be quite another thing to forgive the things those people did. What to do? Forgive the events and actions as they come to mind. As you think of instance after instance, forgive everyone involved as best you can for everything that happened.

For more information visit: www.BeaudryHypnosis.com

How To Release Negativity

by Michelle Beaudry CHt

The past cannot be undone. What you change is how you feel about it.

How Are You Going To Do It? You're tired of being negative. You're ready to change. You need a plan. Read on, my friend, for this is the process of releasing negativity and restoring your spirit. Change is good.

Fear and Anger Are Killers Ask any doctor. The stress of feeling badly all the times can easily lead to medical disorders. Your body and mind are a continuum. In other words, although they are not exactly the same, a great overlap exists between your mind and body, uniting them. Relieve your mental stress and your body will be happier, too. It's time to unburden yourself of everything that has been blocking progress in your life by keeping you attached to an unhappy past.

Feeling Better Is a Process Negativity accumulates in our lives, in our souls, over time. The process of removing it optimally happens in layers. It's best to release as much of each stored neagtive emotion as you can during each sucessive attempt. And of course, you want a safe, private means of release that is as quiet and effective as possible. You can jettison all that old negativity easily and thoroughly by following simple instructions.

Visualization Sports teams have used visualization to improve their level of excellence for decades, visualizing themselves winning trophies, for example. This same technique that so wonderfully installs positive expectation can also be used to eliminate negativity. This means that you can literally let go of old stored feelings of anger, fear, abandonment, embarrassment, and so on, that have been accumulating inside of you all of your life.

Let a Higher Power Help You Do you prefer the word God, Source, Universe, Goddess, Higher Self, or do you have yet another name for that which is all that is? Let your choice reflect your tastes, and let your Higher Power help you. For once you release negative energy, your Higher Power can then transform it into something positive elsewhere in the Universe.

Humans Store Emotions Physically Your body is made of cells, the cells are made of molecules, the molecules are made of atoms, and those are made up of whirling bits of energy; ergo, your body is pure energy. We humans store old memories and emotions in our bodies. That's why the releasing of negativity is a physical, visceral feeling of expelling energy, because energy is what it is, what it all is, what we all are. Ask Einstein.

Examples of What To Release Fear, anger, rage, abandonment, rejection, guilt, shame, worry, blame, numbness, hurt, hatred, jealousy, and disgust are good places to begin. Your unique soul will know which feelings most need releasing, and in which order to do them. You may need to release some of the deepest ones several times to remove ever deeper layers.

What Does It Feel Like? Expelling negativity is not a negative experience, it is a relief. For example, when you let go of a deep layer of fear, you do not feel afraid, you feel relieved of fear. Letting go of rage does not mean that you'll be shouting and thrashing about. Rather, your feelings of rage simply pass out of you, and it is a relief. The old negative feelings are fully released and expelled outwards. Releasing negative emotions needn't involve experiencing the pain inherent in any individual emotion. You've already experienced way too much of that. Getting rid of them feels like what it is: a release. It's like taking a gorilla off of your back. It's removing old baggage that does not serve you anymore. It actually feels good. And you will feel progressively better afterwards each time.

Follow Instructions Through the Steps Get quiet and close your eyes. Be in a quiet, comfortable place without distractions. Vizualize that you are standing in a beautiful place with your arms up, way up, looking up at your Higher Power. Select the negative emotion you first wish to release, and make that happen. Feel it physically leaving your body, sailing up your arms, and then being jettisoned out into space, gone for good, released permanently. Repeat with all the rest of the stored emotions you wish to release. Another approach is to phrase it like this: "I release whatever is obstructing me from my goals," and let the stored emotions let you know what they are as they leave.

Then Restore Your Spirit Once the bad layers are released, it's best to fill up the spaces they left with something wonderfully positive. May I suggest that you begin the restoration of your spirit with Personal Power, Love, Acceptance, and Inner Peace. Personal Power restores your boundaries to normal settings, Love returns you to harmony with all that is, Acceptance assures you that you are wanted and welcomed in the world, and Inner Peace encloses you in a wonderful blanket of secure and peaceful feelings. Simply visualize each of these in turn, whatever they look like to you, and bring each inside of you, merging and bonding with it, soaking in its individual positive energy, then radiating its clarity and serenity everywhere throughout your person. Think of these as permanent upgrades to your soul.

For more information visit: www.BeaudryHypnosis.com

Granulocyte activation in humans is modulated by psychological stress and relaxation.

Stress. 2007 Sep;10(3):271-81.

Keresztes M, Rudisch T, Tajti J, Ocsovszki I, Gardi J. Medical Faculty, Institute of Biochemistry, University of Szeged. Szeged. Hungary.

Our aim was to study the possible relationship between psychological stress and granulocyte activation primarily in healthy students during an examination period (n = 11) and also in chronically anxious patients (n = 15). We employed cell surface markers: lactoferrin, l-selectin, alphaMbeta2-integrin and CD15s and flow cytometry to detect changes in the activation state of granulocytes, with the start of the stressed state in students at the beginning of an examination period, which was associated with elevated blood plasma cortisol level, and following relaxation hypnosis in both students, during their examination term, and patients. The ratios of all four types of marker-carrier granulocytes increased at the start of the examination period in students; an especially dramatic (ca. 5-fold) enhancement was observed in the proportion of lactoferrin-bearing cells relatively to the pre-examination term value. After hypnosis, the percentage of lactoferrin-exposing granulocytes decreased considerably both in students and in patients, by about half; a similar decrease was observed in the ratio of CD15s-carrier cells in patients. No significant alteration was observed during the study in state or trait anxiety levels, and in total or differential leukocyte counts. Thus, granulocyte activation could be associated with stress, while relaxation may facilitate reducing activation of these cells. In both groups of subjects, granulocyte surface lactoferrin appeared to be a sensitive "stress indicator". This needs further evaluation.

Efficacy of hypnotherapy in the treatment of eating disorders.

Research on the efficacy of hypnosis in the treatment of eating disorders has produced mixed findings. This is due in part to the interplay between the characteristics of people with eating disorders and the phenomena of hypnosis. In addition, several authors have noted that methodological limitations in hypnosis research often make evaluation of treatment efficacy difficult. Many of the studies extant provide insufficient information regarding the specifics of the hypnotic intervention(s) to facilitate replication and clinical implementation. Therefore, this paper only reviews literature with replicable methodological descriptions. It focuses on the three primary disorders of interest to clinicians: bulimia nervosa, anorexia nervosa, and obesity. The implications for evaluating treatment efficacy are discussed.

Washington State University. Pullman, Washington. USA. Int J Clin Exp Hypn. 2007 Jul;55(3):318-35.

The Efficacy of Hypnotherapy in the Treatment of Psychosomatic Disorders: Meta-analytical Evidence.

Hypnotherapy is claimed to be effective in treatment of psychosomatic disorders. A meta-analysis was conducted with 21 randomized, controlled clinical studies to evaluate efficacy of hypnosis in psychosomatic disorders. Studies compared patients exclusively treated with hypnotherapy to untreated controls. Studies providing adjunctive standard medical care in either treatment condition were also admitted. Hypnotherapy was categorized into classic (n = 9), mixed form (n = 5), and modern (n = 3). Results showed the weighted mean effect size for 21 studies was d(+) = .61 (p = .0000). ANOVA revealed significant differences between classic, mixed, and modern hypnosis. Regression of outcome on treatment dose failed to show a significant relationship. Numerical values for correlation between suggestibility and outcome were only reported in three studies (mean r = .31). The meta-analysis clearly indicates hypnotherapy is highly effective in treatment of psychosomatic disorders.

Flammer E, Alladin A. Constance University. Konstanz. Germany. Int J Clin Exp Hypn. 2007 Jul;55(3):251-74.

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