Tim Brunson DCH

Welcome to The International Hypnosis Research Institute Web site. Our intention is to provide quality information to clinicians and the general public concerning hypnosis, hypnotherapy, and other mind/body modalities. We intend to expand our coverage to include such topics as Neuro-Linguistic Programming (NLP), energy psychology and medicine, and other related topics. While our intention is to provide quality information derived from valid sources, including peer reviewed literature concerning significant research, this site is not presented as a source of medical or psychological advice. Clinicians wishing to expand their scope of practice or protocols based upon presented information should perform due diligence prior to use. It is our sincere hope to stimulate interest in these topics and to contribute to the evolution of the science of hypnosis. -- Tim Brunson, PhD

Neural correlates of sad faces predict clinical remission to cognitive behavioural therapy in dep.

Currently, there are no neurobiological markers of clinical response for cognitive behavioural therapy (CBT) used in clinical practice. We investigated the neural pattern of activity to implicit processing of sad facial expressions as a predictive marker of clinical response. Sixteen medication-free patients in an acute episode of major depression underwent functional magnetic resonance imaging scans before treatment with CBT. Nine patients showed a full clinical response. The pattern of activity, which predicted clinical response, was analysed with support vector machine and leave-one-out cross-validation. The functional neuroanatomy of sad faces at the lowest and highest intensities identified patients, before the initiation of therapy, who had a full clinical response to CBT (sensitivity 71%, specificity 86%, P = 0.029).

Neuroreport. 2009 Mar 31. Costafreda SG, Khanna A, Mourao-Miranda J, Fu CH. Institute of Psychiatry, King's College London, De Crespigny Park, London, UK.

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Comments
Brian Green's Gravatar Hi Tim. I find these snippets very frustrating. If a report is interesting I would love a link back to the original, though copywrite might not allow direct connection/display.

I am sure I am not alone in claiming statistics and neurobiological natterings are not my strong points.

Failing this, for the more technical jargon loaded articles, a summary of the meaning/relevance of the conclusions or findings is necessary, if I am not to feel teased.
Best wishes, Brian.
# Posted By Brian Green | 7/7/09 10:27 PM
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